Lymphocyte recovery and survival
Over a median follow-up of 28 months, 22 patients died between days +22
and +1 778. The causes of death were relapse (n=14), infection (n=6),
and GvHD (n=2). Factors associated with higher OS were non-malignant
diseases (95% vs. malignant 71%, P <0.001) and BM as
stem cell source (87% vs. SP 57%, P <0.001). ALC and
CD3+CD4+ recovery on D+100 were the lymphocyte parameters associated
with higher survival rates (Fig. 3). In multivariate analyses, ALC
recovery on D+100 showed a protective effect on survival if adjusted for
malignant diseases, except for BM grafts that did not reach statistical
significance (Table 3).