RESULTS
Patient characteristics and clinical outcomes after HSCT are described in Table 1. Although the center is located in the state of Paraná, most patients (59%) were from other Brazilian states, spanning up to 3 400 kilometers.
The cohort consisted of malignant and non-malignant diseases (BM failure syndromes, inborn errors of innate immunity and inborn errors of metabolism). Diagnoses of malignant diseases were acute lymphoblastic leukemia (n=37), acute myeloblastic leukemia (n=10), acute biphenotypic leukemia (n=4), myelodysplastic syndrome (n=2), juvenile myelomonocytic leukemia (n=1) and non-Hodgkin’s Lymphoma (n=1). Bone marrow failure syndromes were acquired severe aplastic anemia (n=14), Fanconi anemia (n=11), Blackfan Diamond anemia (n=7) and dyskeratosis congenita (n=2). Inborn errors of innate immunity included severe combined immunodeficiency (n=9), Wiskott Aldrich syndrome (n=5), hemophagocytic lymphohistiocytosis (n=2), CD40L deficiency (n=1) and Griscelli syndrome (n=1). Adrenoleukodystrophy (n=3) and mucopolysaccharidosis type I (n=1) represented the inborn errors of metabolism.