3.4 | Correlations between CD203c/CD63 response ratio and clinical/laboratory factors
Because basophils in AD patients exhibited characteristic responses to anti-IgE antibody stimulation, we examined the correlations between these expression patterns and clinical/laboratory factors, including EASI score, TARC, LDH, and total serum IgE. There were no correlations between baseline CD203c and factors (Figure S2), baseline CD63 and factors (Figure S3), and CD203c response ratio and factors (Figure S4). CD63 response ratio had moderate negative correlations with EASI score (rs = −.38) and TARC (rs = −.38) (Figure 3 A, B). Although statistically not significant, there was a trend toward a negative correlation between CD63 response ratio and LDH (rs = −.28) (Figure 3 C). CD63 response ratio had a moderate negative correlation with total serum IgE (rs = −.37) (Figure 3 D).