References
  1. Ker K, Edwards P, Perel P, et al . Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta‐analysis. BMJ  2012;344:e3054.
  2. Huang F, Wu D, Ma G, et al.  The use of tranexamic acid to reduce blood loss and transfusion in major orthopedic surgery: a meta‐analysis. J Surg Res 2014;186 (1): 318-27.
  3. Myles PS, Smith JA , Forbes A , et al . Tranexamic acid in patients undergoing coronary-artery surgery. N Engl J Med2017;376 (2):136-148.
  4. Kamhieh Y, Fox H. Tranexamic acid in epistaxis: a systematic review. Clin Otolaryngol 2016; 41 (6):771‐6.
  5. Koizumi M, Ishimaru M, Matsui H, et al . Tranexamic acid and post-tonsillectomy hemorrhage: propensity score andinstrumental variable analyses.  Eur Arch Otorhinolaryngol 2019; 276 (1):249-254.
  6. Benoni G, Bjorkman S, Fredin H. Application of pharmacokinetic data from healthy volunteers for the prediction of plasma concentrations of transexamic acid in surgical patients. Clin Drug Invest 2012;10 (5):280–7.
  7. Lang BH, Yih PCL, Lo CY. A Review of Risk Factors and Timing for Postoperative Hematoma After Thyroidectomy: Is Outpatient Thyroidectomy Really Safe? World J Surg  2012;36 (10):2497–502.
  8. Rosenbaum MA, Haridas M, McHenry CR. Life-threatening neck hematoma complicating thyroid and parathyroid surgery. Am J Surg  2008;195 (3):339–43.
  9. Das A, Chattopadhyay S, Mandal D, et al . Does the preoperative administration of tranexamic acid reduce perioperative blood loss and transfusion requirements after head neck cancer surgery? A randomized, controlled trial. Anesth Essays and Res  2015;9 (3):384‐90.
  10. Fan C, Zhou X, Su G et al. Risk factors for neck hematoma requiring surgical re-intervention after thyroidectomy: a systematic review and meta-analysis. BMC Surg 2019; 19 (1):98
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