Characteristic Study cohort – positive aPL (n=20) Control cohort – negative aPL (n=35) P value
Small for gestational agea 5 (25%) 6 (17.1%) 0.73
Apgar score ≤ 7 at 5-minute 3 (15%) 3 (8.6%) 0.65
Length of NICU hospitalization (days) 34 (16.75-57.75) 30 (19.5-76.5) 0.93
Respiratory distress syndrome (RDS) 10 (50%) 13 (37.1%) 0.52
Intra-ventricular hemorrhage (IVH) 2 (10%) 5 (14.3%) 0.7
IVH 3+4 0 1 (2.9%) 1
periventricular leukomalacia (PVL) 0 0 1
Necrotizing enterocolitis (NEC) 1 (5%) 2 (5.7%) 1
Sepsis 4 (20%) 2 (5.7%) 0.057
Seizures 0 1 (2.9%) 1
Hypoglycemia 1 (5%) 4 (11.4%) 0.64
Hyperbilirubinemia 12 (60%) 21 (60 %) 1
CPAP or mechanical ventilation 7 (35%) 12 (34.3%) 1
Retinopathy of prematurity (ROP) 6 (30%) 2 (5.7%) 0.02
Broncho-pulmonary disease (BPD) 1 (5%) 3 (8.6%) 1
Perinatal death 3 (15%) 1 (2.9%) 0.13