Introduction
Diabetes is generally caused by impairment of the pancreatic β cells.
This in turn leads to declined formation of insulin or enhanced
confrontation to the function of insulin in the peripheral tissues
(Frode and Medeiros, 2008). It is stimulated by both environmental
factors as well hereditary which cause elevated blood sugar level (Wu et
al., 2014). It is a big problem all over the world. Scientists are
trying to solve this problem. Available therapies have side effects and
do not cure the syndrome completely. This is the need of time to search
better alternate for the treatment of diabetes. Phyto-based materials
can prove themselves as a good antidiabetic candidate.
Numerous plants have been confirmed for their antidiabetic activities in
animal models which recommend that the world is probing for new
phyto-based anti-diabetes mediators with fewer side effects (Khan et
al., 2012). Flora is a spring of medications. Various phyto-based
bioactive molecules have been assessed for their proficiency in
controlling several ailments. These medications have therapeutic
potential with no side effects.
Berberis lycium Royle is a plant that has been used to treat
arthritis, back pain, diarrhea, jaundice, piles, internal injuries,
scabies, throat pain, pimples, cracked bones, fever and sun blindness
(Shabbir et al., 2012). In current research B. lycium Royle was
used as antidiabetic agent.