Introduction

Diabetes is generally caused by impairment of the pancreatic β cells. This in turn leads to declined formation of insulin or enhanced confrontation to the function of insulin in the peripheral tissues (Frode and Medeiros, 2008). It is stimulated by both environmental factors as well hereditary which cause elevated blood sugar level (Wu et al., 2014). It is a big problem all over the world. Scientists are trying to solve this problem. Available therapies have side effects and do not cure the syndrome completely. This is the need of time to search better alternate for the treatment of diabetes. Phyto-based materials can prove themselves as a good antidiabetic candidate.
Numerous plants have been confirmed for their antidiabetic activities in animal models which recommend that the world is probing for new phyto-based anti-diabetes mediators with fewer side effects (Khan et al., 2012). Flora is a spring of medications. Various phyto-based bioactive molecules have been assessed for their proficiency in controlling several ailments. These medications have therapeutic potential with no side effects.
Berberis lycium Royle is a plant that has been used to treat arthritis, back pain, diarrhea, jaundice, piles, internal injuries, scabies, throat pain, pimples, cracked bones, fever and sun blindness (Shabbir et al., 2012). In current research B. lycium Royle was used as antidiabetic agent.