CONCLUSION:
The results obtained from our study on 150 subjects support the hypothesis that the use of perioperative treatment with intravenous tranexamic acid, 30 minutes before skin incision, reduces the overall total blood loss, especially if the route of hysterectomy was vaginal. It also reduces the duration of hospital stay and the need for postoperative blood transfusion. No incidences of serious adverse reactions occurred. Thus, tranexamic acid should be considered preoperatively prior to elective benign hysterectomy.
Acknowledgement: The authors are grateful to the Vice Chancellor and Director, PGIMS, Rohtak for support and guidance. We would also like to acknowledge staff members from Department of O.B.G, Pt. B.D. Sharma, PGIMS, Rohtak, India.
Declaration Of Inetrests : The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.