CONCLUSION:
The results obtained from our study on 150 subjects support the
hypothesis that the use of perioperative treatment with intravenous
tranexamic acid, 30 minutes before skin incision, reduces the overall
total blood loss, especially if the route of hysterectomy was vaginal.
It also reduces the duration of hospital stay and the need for
postoperative blood transfusion. No incidences of serious adverse
reactions occurred. Thus, tranexamic acid should be considered
preoperatively prior to elective benign hysterectomy.
Acknowledgement: The authors are grateful to the Vice
Chancellor and Director, PGIMS, Rohtak for support and guidance. We
would also like to acknowledge staff members from Department of O.B.G,
Pt. B.D. Sharma, PGIMS, Rohtak, India.
Declaration Of Inetrests : The authors declare that they have no
known competing financial interests or personal relationships that could
have appeared to influence the work reported in this paper.