Materials and Methods
CENTRAL, MEDLINE/PubMed, Cochrane
Library, and Scopus were systematically searched from inception to May
28, 2020. Studies reporting five or more patients with COVID 19
infection treated venovenous with ECMO were included. The main outcome
assessed was mortality. Baseline, procedural, outcome, and validity data
were systematically appraised and pooled with random-effect methods.
The validity of all the included
observational studies was appraised with the Newcastle Ottawa scale.
Meta-regression and publication bias were tested. This trial was
registered with PROSPERO under registration number CRD42020183861