CD27+IgD+ B cells correlate with SLE patient clinical and immunological features
The associations of the CD27+IgD+ B cell frequencies with demographic and clinical characteristics were analyzed. As shown in Figures 2A–L and Table 3, WBC, Platelet count and serum C3 level positively correlated with CD27+IgD+B cells. We also found the frequencies of these CD27+IgD+B cells were negatively correlated with Serum Creatinine level, SLEDAI and Anti-dsDNA. However, no correlations were noted between the disease duration, ESR, serum C4 level and serum IgA, IgG, IgM level with CD27+IgD+B cells. These data demonstrated that CD27+IgD+B cells were numerically deficient under SLE circumstance.