CD27+IgD+ B cell amounts
correlate with clinical and immunological features in SLE patients
The associations of CD27+IgD+ B cell
amounts with demographic and clinical characteristics were analyzed. As
shown in Figures 2A–L and Table 3, WBC, platelet count and serum C3
levels were positively correlated with
CD27+IgD+B cell amounts. Besides,
CD27+IgD+B cell amounts showed
negative correlations with serum creatinine levels, SLEDAI and
anti-dsDNA. However, no associations of
CD27+IgD+B cells with disease
duration, ESR, serum C4 levels and serum IgA, IgG and IgM levels were
found. The above findings indicated a numerical deficiency of
CD27+IgD+B cells in SLE.