3.2 Left atrial strain and left ventricular strain in patients
with COVID-19 at baseline
GLS and GCS patterns of left ventricle and GLS of left atrium during the
cardiac cycle were reported in Table 3. LA GLS in severe and mild
patients with COVID-19 were lower than
controls(P< 0.05). LV GLS, LV GCS and LA GLS in severe
and mild patients with COVID-19 were lower than
controls(P< 0.05). LVGLS, LVGCS in severe patients were
lower than mild patients(P< 0.05).
Basal, middle and apical segment of circumferential strain (CS) and
longitudinal strain (LS) in severe and mild patients were presented in
Table 4. No significant difference was observed among basal, middle and
apical segments in LV CS and LV LS in severe group. No difference in
three segments in LV CS in mild patients, however, apical LS was higher
than LS in the other two segments in mild patients.
In severe patients with COVID-19(n=20), the value of log (NT-pro BNP)
and log (hs-TnT) were 2.50±0.94 pg/ml and 1.12±0.57 pg/ml respectively.
There was a negative correlation between LV GLS and log TnT-hs as well
as NT pro-BNP in severe patients with COVID -19 (figure 1).
We analyzed the relation between the severity of COVID-19 patients and
LV GLS, LV GCS and LA GLS through ROC curve and defined the mild
condition as positive status (Figure2).The results showed that the URC
of LV GLS, LV GCS and LA GLS to predict the severity were
0.698(0.543-0.826), 0.758(0.607-0.873) and 0.782(0.634-0.891)
respectively. LV GLS, LV GCS and LA GLS may had a low or medium
diagnostic performance for the severity of COVID-19 patients (allP <0.05).