3.2 Left atrial strain and left ventricular strain in patients with COVID-19 at baseline
GLS and GCS patterns of left ventricle and GLS of left atrium during the cardiac cycle were reported in Table 3. LA GLS in severe and mild patients with COVID-19 were lower than controls(P< 0.05). LV GLS, LV GCS and LA GLS in severe and mild patients with COVID-19 were lower than controls(P< 0.05). LVGLS, LVGCS in severe patients were lower than mild patients(P< 0.05).
Basal, middle and apical segment of circumferential strain (CS) and longitudinal strain (LS) in severe and mild patients were presented in Table 4. No significant difference was observed among basal, middle and apical segments in LV CS and LV LS in severe group. No difference in three segments in LV CS in mild patients, however, apical LS was higher than LS in the other two segments in mild patients.
In severe patients with COVID-19(n=20), the value of log (NT-pro BNP) and log (hs-TnT) were 2.50±0.94 pg/ml and 1.12±0.57 pg/ml respectively. There was a negative correlation between LV GLS and log TnT-hs as well as NT pro-BNP in severe patients with COVID -19 (figure 1).
We analyzed the relation between the severity of COVID-19 patients and LV GLS, LV GCS and LA GLS through ROC curve and defined the mild condition as positive status (Figure2).The results showed that the URC of LV GLS, LV GCS and LA GLS to predict the severity were 0.698(0.543-0.826), 0.758(0.607-0.873) and 0.782(0.634-0.891) respectively. LV GLS, LV GCS and LA GLS may had a low or medium diagnostic performance for the severity of COVID-19 patients (allP <0.05).