3.2 PTUPB improves plasma lipids in obese ZSF1 rats
Plasma cholesterol, triglycerides, NEFA, and LDL-cholesterol were 70-90% higher in obese ZSF1 rats compared to lean ZSF1 rats. Interventional PTUPB treatment markedly improved the lipid profile of obese ZSF1 rats and reduced plasma lipids to levels similar to lean ZSF1 rats. Interestingly, enalapril treatment did not affect the lipid profile of obese ZSF1 rats and the plasma lipid levels remained elevated in obese ZSF1 rats (Figure 2).