Conclusion:
Although it appears that dipyrone exhibits a profile suitable for use in
children, more well-designed studies are needed to establish its role in
the postoperative period of tonsillectomy due to the scarcity of
randomised clinical trials evaluating its postoperative analgesic
effect. The argument for the occurrence of agranulocytosis does not seem
strong enough to justify the abandonment of these studies, because its
incidence is very low, mainly in children, at least in Latin America.
Specially in low-income countries, its use is attractive because it has
a low cost and can be used intravenously, an advantageous feature in the
postoperative period of tonsillectomy where odynophagia is universal.