Study Outcomes:
The primary outcome of our study was to assess rate of new pacemaker
implantation in patients discharged following TAVR. Secondary outcomes
include:
- Primary indication for pacemaker implantation resulting in readmission
post TAVR.
- Time from index admission for TAVR to readmission for pacemaker
placement post discharge (d-PPMI)
- Clinical factors differentiating patients who received delayed
pacemaker implant post TAVR (d-PPMI) from patients with no pacemaker
from discharge up to 6 months of follow-up (o-PPMI)
- Clinical factors differentiating patients who received delayed
pacemaker implant post TAVR (d-PPMI) from patients who underwent
pacemaker implantation during index admission for TAVR (i-PPMI)
Statistical Analysis:
All analyses were performed on weighted data and were performed
accounting for complex sampling design as recommended by HCUP.
Categorical and continuous variables were reported as percentages and
mean ± standard error (SE), respectively. Dichotomous outcomes were
reported as proportions and compared with using the Pearson χ2 test to
evaluate for univariate associations. In-hospital mortality was modelled
into a multivariate logistic regression model adjusting for
demographics, co-morbidities, complications and treatment
characteristics and reported as adjusted odds ratios (aOR) and their
95% confidence intervals. All data extraction and analyses were
performed using SPSS (Version 15; College Station, TX).