Study population
Details of 42 MPS patients were reviewed at the Department of
Pediatrics, MacKay Memorial Hospital, Taipei between January 2010 and
June 2020. They were categorized as MPS I (7 patients, 16.7%), MPS II
(15 patients, 35.7%), MPS IIIB (8 patients, 19.0%), MPS IVA (9
patients, 21.4%), and MPS VI (3 patients, 7.2%). There were 30 males
and 12 females, with a median age of 20.5 years (range 5 to 40 years).
Patients consulted an otorhinolaryngologist for an opinion on the need
for surgery at a median age of 5.5 years. All patients were receiving
ERT, except MPS III patients, and all were alive at the time of study.