Results and Discussion

Table 1 shows the design variables X and their ranges. The X were defined as 24 variables based on equipment and operating conditions, such as the flow rate, reactor specifications, and distillation column specifications. Table 2 show Y and their target ranges. The Y were defined as eight variables, such as reactor inlet composition, conversion ratio, and product limitations. The reactor inlet concentration and conversion ratio were set because of explosion limits.
Table 1. The design variables X and their ranges