Current challenges
Although impressive progress has been made in revolutionizing the
landscape of anti-cancer treatment through the development of cellular
therapy, many challenges remain, such as ensuring successful
leukapheresis and CAR T cell manufacturing, non-response and disease
relapse, and managing its unique toxicity profile. Continued insights
into these barriers will allow us to maximize the potential benefit of
this powerful therapy with the goal of extending the application of CAR
T cell therapy beyond B cell malignancies.