Results
3768 patients were included during the study period, 1906 from the ED
and 1862 other inpatients. Overall, 806 (21%), 755 (20%), and 28 (1%)
samples were positive for SARS-CoV-2, any other respiratory viruses, or
atypical bacteria, respectively. The SARS-CoV-2 wave struck from
February to April with a peak incidence between mid-March and
early-April. At this time, rhinoviruses, human coronaviruses,
adenoviruses, or parainfluenza viruses were still circulating, but most
of the seasonal respiratory virus epidemic was already gone, especially
influenza (cf Figure 1). Among the 806 SARS-CoV-2-positive patients, 42
(5%), 7 (1%), and 6 (1%) also presented one, two other viruses and
atypical bacteria, respectively, and 61 (8%) non-SARS-CoV-2 patients
positive by mPCR showed viral co-infections. Most frequently associated
viruses were rhinoviruses (17), common human coronaviruses (15),
adenoviruses (7), parainfluenza (5), metapneumoviruses (4), influenza
(4), and RSV (2) and other pathogens (7). The temporal distribution of
pathogens is depicted below (Figure). When comparing ED patients with
SARS-CoV-2 either alone (n= 249) or associated (n=33) , they presented
similar age, symptoms, vital signs measurements, or comorbidities,
except for fever (p=0.013) and headaches (p=0.048). Among those
co-infected patients, 0 (0%) were hospitalized in ICU at day 1 versus
64/249 (26%) patients with only a SARS-CoV2 infection, p=0.78. 5 (2%)
among the co-infected patients died during hospitalization, and 49
(20%) with only a SARS-CoV2 infection, p=0.78.