Variables
CV for all subjects (%)
Positive bronchial provocation test
Negative bronchial provocation test
P value
n - 170 522 -
Age, years 33.79 43.90 (14.56) 43.80 (14.90) 0.980
Male, n (%) - 53 (31.18%) 203 (38.89%) 0.082
BMI, kg/m2† 14.88 22.94 (2.99) 23.51 (3.61) 0.075
Past smoking history (n / %) - 31 (18.24) 97 (18.58) .204
FVC, % predicted 11.82 101.10 (10.85) 101.60 (12.36) 0.993
FEV1, % predicted 11.95 99.33 (11.01) 105.50 (12.49) < .001
FEV1/FVC, % 6.72 82.55 (5.51) 86.87 (5.45) < .001
FEV3/FVC, %†§ 1.98 97.65 (2.26) 98.47 (1.76) 0.001
PEF, % predicted 16.27 90.61 (13.93) 96.21 (15.65) < .001
FEF25%, % predicted 21.63 90.08 (15.87) 100.80 (22.10) < .001
FEF50%, % predicted 25.55 77.26 (17.74) 98.20 (23.24) < .001
FEF75%, % predicted 31.84 74.91 (22.43) 101.20 (60.72) < .001
FEF25%-75%, % predicted 25.51 75.95 (17.64) 97.01 (22.76) < .001
Small-airway dysfunction - 104 132 < .001
R5-R20, kPa·L-1·s†¶ 94.65 0.13 (0.11) 0.10 (0.09) < .001
X5, kPa·L-1·s†¶ 97.54 -0.12 (0.10) -0.10 (0.08) < .001
Fres, L-1·s†¶ 42.52 17.53 (9.02) 14.24 (5.03) < .001
FENO, ppb 94.96 59 (28- 98) 24 (15 - 45) < .001
EOS in blood, % 95.46 5.16 (1.70- 7.73) 3.37 (1.20 - 4.40) < .001
EOS in blood, cells/μl 106.10 370.6 (120 - 530) 237.2 (80 - 302.5) < .001
PD20, mg 130.68 0.079 (.026- .369) - -