Figure 3 Showing viral dynamics (A,D, G) and infected cells,(B,E,H representing newly infected cells; and C,F,I represent the cumulative infected proportions as a proxy of tissue damage over time). In A-C penetration of the target cells is assumed to be optimal. Grey represents infection without antivirals, purple represents infection under moderately effective antiviral (60% inhibition) and green represents highly effective antiviral (90% inhibition). In D-F, penetration and/or inhibition are suboptimal: light orange represents 50% penetrance coupled with 90% inhibition and light brown represents 100% penetration with 60% inhibition. In G-I, the model includes basic innate immunity activated by infected cells density. Again, grey represents infection without antivirals, purple represents infection under moderately effective antiviral (60% inhibition) and green represents highly effective antiviral (90% inhibition).