Conclusion
Any patient with a malignancy who develops a neuromuscular syndrome should be investigated for the possibility of paraneoplastic syndrome. Patients with PV positive for JAK2 mutation can develop MG as a paraneoplastic syndrome, in the absence of thymoma. PV shows good response to hydroxyurea therapy and MG to steroid plus cholinergic therapy. Interferon-alpha is an upcoming modality for cytoreductive therapy in PV, which is also evidenced to bring about remission in MG.