Simultaneous intraocular and cutaneous extranodal NK/T cell lymphoma
refractory to multiple therapies including pembrolizumab
Peter Mallal1, Benhur Ammanuel2,
Rohen White3, Chris Kennedy4, Chan
Yoon Cheah1,5,6
1Department of Haematology, Sir Charles Gairdner
Hospital, Nedlands, WA, Australia; 2Department of
Anatomical Pathology, Pathwest Laboratory Medicine, Nedlands, WA,
Australia; 3Department of Radiation Oncology, Sir
Charles Gairdner Hospital, Nedlands, WA, Australia;4St John of God Eye Clinic, Subiaco, WA, Australia;5Department of Haematology, Pathwest Laboratory
Medicine, Nedlands, WA, Australia; 6Medical School,
University of Western Australia, Crawley, WA, Australia.
corresponding author:
Peter Mallal
Department of Haematology
Sir Charles Gairdner Hospital
Hospital Avenue
Nedlands, WA, Australia
email: petermallal93@gmail.com
word count: 1776
reference count: 38
figures: 2
Keywords: Haematology, Lymphoma, ocular lymphoma, ENKL, ENKTL,
Pembrolizumab
Key Clinical Message: Floaters or visual disturbance in a patient with
ENKL should prompt evaluation for possible vitreoretinal involvement.
Lymphoma with ocular involvement should be treated aggressively and in
most cases heralds CNS involvement.