Author’s contributions
Dr. Melero, Dr. Romecín and Dr. Iyú performed all the experiments except those done at the Laboratory of Flow Cytometry-Coulter Cytometry Center and Related Techniques in Valencia, Dr. García-Bernal performed the calcium experiments, Ms. García-Navarro was the technician lab responsible for the optimal maintainance of all the equipment and reagents, Dr. Moraleda and Dr. García-Candel were the clinicians responsible for the management of all patients, Dr. Atucha and Dr. García-Candel were the main designer of all protocols and study, and Dr. García-Estañ was the main writer of the manuscript.