Methods
Study
Participants
Study participants were recruited from the St. Jude Lifetime Cohort
Study (SJLIFE),20 a retrospective cohort of childhood
cancer survivors who participate in prospective medical assessments. The
cohort was initiated in 2007 and includes survivors of childhood cancer
who are ≥5 years post-diagnosis of a pediatric cancer treated at St.
Jude Children’s Research Hospital. For the current study, survivors
enrolled in SJLIFE who were ≥18 years of age and ≥10 years post
diagnosis were recruited for a randomized controlled trial focused on
sleep and cognition. We identified and screened 3,348 potentially
eligible SJLIFE participants. Among these survivors, 562 refused
participation in the intervention and 1,875 did not meet initial study
specific inclusion/exclusion criteria (see Supplementary Table S1
intervention inclusion/exclusion criteria). This resulted in 911
participants who completed baseline evaluations to confirm eligibility
for the intervention study and who form the study population for the
current analysis. All participants provided written informed consent and
the study was approved by the Institutional Review Board at St. Jude
Children’s Research Hospital.
Measures