Enzyme
source
|
Km
|
Vmax
|
CLint
|
CLint fold
(CYP2J2 / CYPs)
|
HLM |
22.81
± 2.370
|
91.28 ± 3.233 |
4.002 |
− |
CYP2J2 |
19.37 ± 1.932 |
753.9 ± 19.97 |
38.92 |
− |
CYP3A4 |
46.98 ± 4.800 |
47.24 ± 1.843 |
1.006 |
38.68 |
CYP2D6 |
98.78 ± 8.839 |
59.94 ± 2.597 |
0.607 |
64.11 |
CYP4F3 |
75.19 ± 5.312 |
29.42 ± 0.898 |
0.391 |
99.54 |