Results
Of the 244 acne patients participating in the study, 173 were women
(77.2%). The mean age of the patients was 21.0 ± 3.5 years. There was
no difference between genders in terms of age (p: 0.263). The changes in
laboratory parameters in the 3rd month of ISO
treatment compared to the 0th month are presented in
Table 1. After treatment, there was a statistically decrease in
neutrophil count and an increase in lymphocyte count (p: 0.002, p:
0.011; respectively). Accordingly, there was a statistically significant
decrease in NLR (p: 0.001). A statistically significant increase in
total cholesterol, LDL, triglyceride levels, and a significant decrease
in HDL levels were found (p < 0.001). It was noteworthy that
MHR and SUA levels increased significantly (p: 0.042, p: 0.010;
respectively). Correlations of SUA levels with laboratory parameters
before and after treatment were presented in Table 2. SUA and hemoglobin
levels were moderately positively correlated (r: 0.439, p <
0.001 and r: 0.473, p < 0.001; respectively). Although there
was no significant relationship between SUA level with total
cholesterol, LDL, and triglyceride levels before treatment, a weakly
significant relationship was found between them after treatment (Table
2). The correlation between MHR and SUA levels before and after
treatment was statistically significant (r: 0.157, p: 0.048; r: 0.212,
p: 0.012; respectively).