2.2. Sequence alignment
The online sequence alignment service of The European Molecular Biology
Open Software Suite (EMBOSS) was used to determine the protein
similarity and identity percentages of the SARS-CoV-2, SARS-CoV, and
RaTG13. The matrix of the sequence alignment was EBLOSUM62 and the gap
and extend penalties were 14 and 4, respectively. The sequence alignment
service of the EMBOSS is available at:
https://www.bioinformatics.nl/cgi-bin/emboss/matcher.