Outcomes
The primary outcome was cardiac remodeling within 1 year
postoperatively. Functional, anatomical, and hemodynamic assessments
included preoperative and postoperative LVEF, LV internal dimension in
diastole (LVIDd), LA size (mm), LA volume index
(ml/m2), MV area (MVA) (cm2), and MV
peak and mean gradients. Secondary outcomes include mortality at any
time postoperatively, postoperative stroke, myocardial infarction (MI),
reoperation of the MV, and rehospitalization. Both during admission and
following discharge for the index procedure, outcome data were collected
and identified based on admitting diagnosis for any readmission. MI was
defined as the primary diagnosis of ST-segment elevation MI (STEMI) or
non-STEMI for readmission any time during the follow-up period. Stroke
was defined as the primary diagnosis at readmission at any point during
the follow-up period. Reoperation of the MV was defined as MVR, surgical
repair, or repair of complications originating from the index procedure.
New-onset AF was defined as AF arising after the index procedure with no
prior history of AF. Residual MR included moderate or severe MR within 1
year postoperatively.