Study Cohort
This study included patients with severe MV disease that underwent MVR
at the University of Alberta Hospital between January 1, 2004, and
December 31, 2018 (Figure 1). Exclusion criteria included repair of the
MV or if data was incomplete (n=1673), if they were in a critical
preoperative state (n=24) (need for intra-aortic balloon pump, acute
renal failure requiring dialysis, respiratory failure requiring
ventilation), or if there was a preoperative diagnosis of endocarditis
(n=96). A total of 1072 patients were included consisting of 476 males
and 596 females (Figure 1). After propensity matching, 314 males and 314
females were included. Patients were followed for a maximum of 16 years
with a median follow-up of 8.4 years.