INTRODUCTION:
Duchenne Muscular Dystrophy is an X-linked inherited disorder and the most common fatal muscle disease in pediatric patients, affecting one of 3,000 - 6,000 male births. It is caused by a mutated encoding gene that produces a dysfunctional dystrophin protein, resulting in progressive degeneration of cardiac and striated muscles. DMD diagnosis is sustained by family history, typical clinical presentation, and altered laboratory findings, such as elevated transaminases and creatine kinase, however, is only confirmed through the absence of dystrophin in immunohistochemical tests of muscle biopsy or in genetic tests by detecting mutations in the DMD gene 1,2. The first symptoms usually manifest at an early age, with weakness of lower limbs and shoulders, psychomotor developmental delay, calf hypertrophy, and, later, with signs of cardiac and ventilatory muscle impairment