4 CONCLUSION
According to the obtained results, it was possible to conclude that the
plant species studied presented high concentrations of total polyphenols
and low concentrations of flavonoids when compared to the literature.
Phenolic compounds are mainly responsible for the therapeutic effects of
artichoke, suggesting a possible indication as complementary treatment
for chronic diseases non transmissibles. However, additional
investigation about the rational use of this extract as complementary
treatment, research of other phytochemical markers are necessary to
establish safety recoveries that improve the rational quality of
individuals who have chronic disease non transmissible.
The treatment of non-diabetic animals with the artichoke extract was
capable of controlling the glycemic levels in short-term and
medium-term, demonstrating a better analysis of lipidic profile. Despite
these animals showing renal lesions installed due to the creatinine
increase, it was not observed reduction of creatinine in diabetic rats
non-treated with the artichoke extract. The somatory of the beneficial
effects showed in this study, surgery a possible complementary treatment
to Diabetes mellitus with artichoke crude extract