4 CONCLUSION
According to the obtained results, it was possible to conclude that the plant species studied presented high concentrations of total polyphenols and low concentrations of flavonoids when compared to the literature. Phenolic compounds are mainly responsible for the therapeutic effects of artichoke, suggesting a possible indication as complementary treatment for chronic diseases non transmissibles. However, additional investigation about the rational use of this extract as complementary treatment, research of other phytochemical markers are necessary to establish safety recoveries that improve the rational quality of individuals who have chronic disease non transmissible.
The treatment of non-diabetic animals with the artichoke extract was capable of controlling the glycemic levels in short-term and medium-term, demonstrating a better analysis of lipidic profile. Despite these animals showing renal lesions installed due to the creatinine increase, it was not observed reduction of creatinine in diabetic rats non-treated with the artichoke extract. The somatory of the beneficial effects showed in this study, surgery a possible complementary treatment to Diabetes mellitus with artichoke crude extract