Data sources
Two health benefit plans represented the data sources: Commercial for working population and their families (< 65 years) and Medicare for the elderly (> 65 years). The Commercial plan is rooted in private insurance, while Medicare is a government-sponsored program and managed by healthcare organizations. At the beginning of the study (January 1, 2016 to May 1, 2019), only individuals with both medical/pharmacy benefits were included with at least six months of benefits or more in the prevalence study. To ensure that members in the Commercial plan would not exceed 65 years at the end of the study, only individuals aged 61 years or less participated. The study population included 7,429,464 persons (3,733,874 females and 3,695,590 males) in the Commercial plan, with 914,528 individuals in the Medicare plan (524,573 females and 389,855 males). In total, this investigation spanned over a period of up to 3 years and 10 months (from January 1, 2016 to October 31, 2019).