Clinical data
The medical records of POST-TEXT III and IV hepatoblastoma patients
admitted to Children’s Hospital of Fudan University from January 2009 to
June 2019 were analyzed retrospectively. The study was approved by the
institution scientific and ethics committee of our hospital. Informed
consent was obtained from all legal guardians of the children who agreed
to participate in this study. The staging of hepatoblastoma is based on
the
pretreatment
extent of disease (PRETEXT) system. Tumor extensions before and after
neoadjuvant chemotherapy were referred to as PRETEXT and POST-TEXT,
respectively. Variables studied included age at diagnosis, gender,
neoadjuvant and adjuvant chemotherapy regimens, a-fetoprotein (AFP)
levels, type of operation, operative time, amount of blood loss,
histology, and clinical outcomes.