Study design
This was a multicentric retrospective analysis of prospectively
collected data from 10 cardiac units in Italy (December 2010 to December
2019), based upon a predefined and anonymized extraction sheet. All
centres entered cardiac surgery-related data into a common registry that
was subject to review by a centralized clinical governance unit who
checked data for accuracy and completeness monthly.
. Patients undergoing elective, urgent or emergent isolated valve
intervention (MVS or SAVR or TAVR) were included in the analysis.
Patients with concomitant coronary artery disease necessitating surgical
or percutaneous revascularization were excluded. For the surgical
strata, both standard sternotomy and minimally invasive approach were
included.
Centre specification and inclusion / exclusion criteria are given inSupplementary Material .