Introduction
Pulmonary arterial hypertension (PAH) is a possible complication and a significant source of morbidity and mortality in patients with thalassemia syndromes [1]. Pathogenic mechanisms of PAH in thalassemia are multifactorial. Chronic hemolysis, reduced nitric oxide bioavailability, chronic hypercoagulable states and various disease-directed therapies may play important roles in its development [2]. Even though chronic thromboembolic pulmonary hypertension (CTEPH) is a well-recognized cause of PAH in patients with β-thalassemia, surgical management of CTEPH has only rarely been reported in such cases thus far [3, 4]. We report here the case of a patient with β-thalassemia complicated with CTEPH who underwent successful surgical pulmonary thrombo-endarterectomy (PTE). Approval for writing this report was obtained from the local ethics committee of our institution, and obtaining individual consent was waived due to the retrospective nature of the study.