Figure Legends
Figure
1. Basic Information of the patient.
(A)
The treatment timelines, and images of brain, liver and lung metastases.
AC, doxorubicin/cyclophosphamide; TH, paclitaxel/trastuzumab; DT,
radiotherapy; G+X+H, gemcitabine/xeloda/trastuzumab; L+Cap,
Lapatinib/capecitabine; WBRT, whole brain radiation therapy; NVB,
navelbine; EVE, everolimus; CBP, Carboplatin. (B) Somatic mutations of
ctDNA detected by 425 cancer-related genes sequencing. AF, allele
frequency.
Figure
2. Characteristics of PIK3R1 mutations from
cBioPortal.
The data is analyzed by
www.cbioportal.org in all cancer
types (A, B) and the breast cancer cohorts (D, E). (C) Malignant tumor
patients with PIK3R1E541_Y542del are summarized in
the table. Location of PIK3R1E541_Y542del is
indicated in Figure 2B (red arrow).