Figure Legends
Figure 1. Basic Information of the patient.
(A) The treatment timelines, and images of brain, liver and lung metastases. AC, doxorubicin/cyclophosphamide; TH, paclitaxel/trastuzumab; DT, radiotherapy; G+X+H, gemcitabine/xeloda/trastuzumab; L+Cap, Lapatinib/capecitabine; WBRT, whole brain radiation therapy; NVB, navelbine; EVE, everolimus; CBP, Carboplatin. (B) Somatic mutations of ctDNA detected by 425 cancer-related genes sequencing. AF, allele frequency.
Figure 2. Characteristics of PIK3R1 mutations from cBioPortal.
The data is ana­lyzed by www.cbio­portal.org in all cancer types (A, B) and the breast cancer cohorts (D, E). (C) Malignant tumor patients with PIK3R1E541_Y542del are summarized in the table. Location of PIK3R1E541_Y542del is indicated in Figure 2B (red arrow).