Conclusion:
The increased incidence of ischemic stroke was frequently encountered
among patients with ARDS and a significant inflammatory response. We
hypothesized that the underlying pathophysiology could be related to the
considerable inflammation, deranged coagulation, and viral cell invasion
through endothelial ACE2 receptors; this finding warranted the
suggestion of a full dose of anticoagulation for the hospitalized
patient with moderate to severe COVID-19 pneumonia. Such observations
need further studies to define the exact mechanism by which SARS-COV-2
induces ischemic stroke.