Abstract:
The novel severe acute respiratory syndrome coronavirus (SARS-COV-2)
affects different people in different ways. Most infected people will
develop mild to moderate respiratory flu-like illness and recover
without the need for hospitalization. However, one of the not uncommonly
observed extrapulmonary associations with SARS-COV-2 is developing
severe large-vessel acute ischemic stroke. Moreover, COVID-19
virus-linked cerebrovascular accidents (CVA) were more severe and
resulted in a higher risk for severe disability and mortality following
acute insults. Although the pathophysiology is not fully understood, the
neuro-targeting nature of SARS-COV-2 due to the vascular injury and the
hyperimmune response were plausible proposed mechanisms. Further
research is warranted to have a deep insight into the possible
mechanisms. Herein, we review the current literature and describe five
patients we have encountered during the SARS-COV-2 viral pandemic.