However it is of worth, mentioning that recombinant Para-thyroid hormone besides its more effectiveness is prescribed very less in Pakistan because of its increased cost of therapy and is not easily available around the country, whereas bisphosphonates with comparative less effectiveness is prescribed more rapidly due to affordable cost of the entire therapy and easy availability. Due to the developing status of Pakistan, it's unable to formulate recombinant human Para-thyroid hormone subcutaneous injection and hence import the drug.