Patterns Categories of PRAL and NEAP scores Categories of PRAL and NEAP scores Categories of PRAL and NEAP scores Categories of PRAL and NEAP scores
Tertile 1 Tertile 2 Tertile 3 P trend
PRAL (<-14.28 mEq/d) (-14.28 to 2.57 mEq/d) (> 2.57 mEq/d)
No. cases/controls 12/28 20/20 28/12
Crude 1.00 (Ref ) 2.33(0.93-5.84) 4.88(2.22-13.41) 0.001
Model 1 1.00 (Ref ) 1.78(0.62-5.12) 3.94(1.37-1131) 0.01
Model 2 1.00 (Ref ) 1.72(0.89-5.04) 3.94(1.32-11.71) 0.01
Model 3 1.00 (Ref ) 2.07(0.68-6.32) 3.42(1.11-8.65) 0.03
NEAP (<38.09 mEq/d) (38.09 to 49.97 mEq/d) (> 49.97 mEq/d)
No. cases/controls 12/28 20/20 28/12
Crude 1.00 (Ref ) 2.33(0.93-5.84) 5.44(2.09-14.17) 0.001
Model 1 1.00 (Ref ) 1.64(0.59-4.58) 4.25(1.49-12.10) 0.01
Model 2 1.00 (Ref ) 1.55(0.55-4.39) 4.29(1.45-12.71) 0.01
Model 3 1.00 (Ref ) 1.63(0.56-4.79) 3.88(1.26-9.55) 0.02
PRAL, potential renal acid load; NEAP, net endogenous acid production. a Multivariate logistic regression was used. Data are presented as odds ratio (95% confidence interval). Model 1: Adjusted for age, body mass index, energy intake, smoking, and physical activity. Model 2: Adjusted for confounders in model 1 plus ethnicity, job, and education. Model 3: Adjusted for confounders in model 2 plus drug usage (Antihyperlipidemic drugs, antihypertensive drugs, and aspirin). PRAL, potential renal acid load; NEAP, net endogenous acid production. a Multivariate logistic regression was used. Data are presented as odds ratio (95% confidence interval). Model 1: Adjusted for age, body mass index, energy intake, smoking, and physical activity. Model 2: Adjusted for confounders in model 1 plus ethnicity, job, and education. Model 3: Adjusted for confounders in model 2 plus drug usage (Antihyperlipidemic drugs, antihypertensive drugs, and aspirin). PRAL, potential renal acid load; NEAP, net endogenous acid production. a Multivariate logistic regression was used. Data are presented as odds ratio (95% confidence interval). Model 1: Adjusted for age, body mass index, energy intake, smoking, and physical activity. Model 2: Adjusted for confounders in model 1 plus ethnicity, job, and education. Model 3: Adjusted for confounders in model 2 plus drug usage (Antihyperlipidemic drugs, antihypertensive drugs, and aspirin). PRAL, potential renal acid load; NEAP, net endogenous acid production. a Multivariate logistic regression was used. Data are presented as odds ratio (95% confidence interval). Model 1: Adjusted for age, body mass index, energy intake, smoking, and physical activity. Model 2: Adjusted for confounders in model 1 plus ethnicity, job, and education. Model 3: Adjusted for confounders in model 2 plus drug usage (Antihyperlipidemic drugs, antihypertensive drugs, and aspirin). PRAL, potential renal acid load; NEAP, net endogenous acid production. a Multivariate logistic regression was used. Data are presented as odds ratio (95% confidence interval). Model 1: Adjusted for age, body mass index, energy intake, smoking, and physical activity. Model 2: Adjusted for confounders in model 1 plus ethnicity, job, and education. Model 3: Adjusted for confounders in model 2 plus drug usage (Antihyperlipidemic drugs, antihypertensive drugs, and aspirin).