Results

Five participants (two cases and three controls) did not include in the analyses due to poor response to FFQ, and finally 120 participants (60 cases and 60 controls) included in final. The participant characteristics across the tertiles of PRAL and NEAP are shown inTable 1 . It was observed that by increasing the score of PRAL, the BMI (P = 0.03) and physical activity (P = 0.04) of individuals decreased. Through tertiles of NEAP, the number of antihypertensive drug users were significantly increased (P = 0.02) and higher education level was associated with decreased NEAP score (P = 0.04). In addition, there was a direct association between the tertiles of both NEAP (P =0.01) and PRAL (P = 0.003) and the age of participants. Table 2 presents the mean intake of food groups and nutrients across the tertiles of PRAL and NEAP. It shows that higher PRAL (P= <0.001) and NEAP (P= <0.001) scores were significantly associated with higher dietary protein intake. Moreover, higher PRAL and NEAP scores were significantly associated with greater vitamin B3 (PRAL; p= 0.003, NEAP; p= 0.002), vitamin B12 (PRAL; p= 0.001, NEAP; p= 0.001), zinc (PRAL; p= 0.01, NEAP; p= 0.01), grains (PRAL; p= 0.01, NEAP; p= 0.02), fish/poultry (PRAL; p= <0.001, NEAP; p= 0.002) and red/processed meats (PRAL; p= <0.001, NEAP; p= <0.001) intake. However, increased PRAL and NEAP scores were significantly associated with lower dietary fiber (PRAL; p= <0.001, NEAP; p= <0.001), vitamin A (PRAL; p= 0.01, NEAP; p= 0.04) , vitamin E (PRAL; p= <0.001, NEAP; p= <0.001), vitamin K (PRAL; p= <0.001, NEAP; p=<0.001), vitamin C (PRAL; p= <0.001, NEAP; p=<0.001), vitamin B6 (PRAL; p= 0.01, NEAP; p=0.02), vitamin B9 (PRAL; p= <0.001, NEAP; p= <0.001), potassium (PRAL; p= <0.001, NEAP; p=<0.001), calcium (PRAL; p= <0.001, NEAP; p=<0.001), magnesium (PRAL; p= <0.001, NEAP; p=<0.001), fruits (PRAL; p= <0.001, NEAP; p=<0.001) and vegetables (PRAL; p= <0.001, NEAP; p= <0.001). Additionally, higher NEAP score was linked with less total fat intake (p=<0.001) and higher PRAL score was associated with less intake of phosphorous (p= 0.04) and dairy (p= 0.21). The odds ratios (OR) of PC according to tertiles of PRAL and NEAP are presented in Table 3 . Our crude results manifested that being in the third compared to the first tertiles of PRAL (OR=5.44; 95% CI= (2.09-14.17)) or NEAP (OR=4.88; 95% CI= (2.22-13.41)) increased the risk of PC. Moreover, after adjusting for potential confounders (energy intake, smoking, physical activity, ethnicity, job, education, anti-hyperlipidemic drugs, antihypertensive drugs, and aspirin), being in the third compared to the first tertiles of PRAL (OR=3.42; 95% CI= (1.11-8.65)) or NEAP (OR=3.88; 95% CI= (1.26-9.55)) was significantly associated with increased risk of PC.