Conclusions
Host factors, like neutropenia, relapse of disease, and hematologic
malignancies, are determinant in the survival times of children affected
with IFD. Pulmonary fungal infections, most caused by filamentous fungi,
are also responsible for shortening survival times in these patients.
Fungemia, most caused by Candida species, seems to lead to a
better survival. Fluconazole prophylaxis does not appear to affect the
hazards of death from IFD.
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Legend of figure 1:
Figure 1. Kaplan Meier survival curves in IFI, for the diagnoses of
leukemia, presence of neutropenia, pulmonary fungal infections and
fungemia by Candida species. P-values refer to the log rank test.