Conflict of interest statement
BL Aalbers has assisted in clinical trials for Vertex as a sub-investigator.
KM de Winter-de Groot works as an investigator in clinical studies for Vertex.
HGM Arets is member of the advisory board, speaker and investigator in several clinical studies for Vertex.
CK van der Ent reports grants from Vertex, outside the submitted work.
HGM Heijerman has provided assistance to Vertex pharmaceuticals, the manufacturer of lumacaftor/ivacaftor, as member of the advisory board, speaker and investigator in clinical studies.