Questionnaire
A short four-item questionnaire is administered to parents and patients ≥7 years of age, if willing and able, at the start and end of SPRINT to inquire about patients’ subjective symptoms. Questionnaire inquiries include, “In the last 7 days: How often has your child felt tired? How often has your child felt sad? How often has your child felt nervous? How often has your child had pain?” Response options consist of “never”, “rarely”, “sometimes”, “often”, and “always”. For statistical analysis, responses were converted to nominal values, with “never” assigned as 5 to “always” as 1.