Findings from the meta-analysis on total water intake and CVD mortality:
Five cohort studies examined the association between total water intake and risk of CVD mortality[5, 6, 14-16]. These studies included a total of 91051 participants among them 7107 mortality cases were found. The summary effect size for CVD mortality, comparing the highest and lowest total water intakes, was 0.84(95% CI: 0.77-0.93, P<0.001), indicating a significant inverse association between total water intake and risk of CVD mortality (Figure 4 ). No significant heterogeneity among the studies was observed (I2 = 0%; P = 0.76).