Figure legends:
Figure 1 : Brain MRI revealed multiple lesions in the bilateral cerebellar hemispheres, thalamus, basal ganglia region, lateral ventricle, radial coronal, center semicovale, bilateral frontoparietal temporal lobe and right occipital lobe. a: T1 weighted imaging (T1W1) revealed slightly low signal. b: T2 weighted imaging (T2WI) showed high signal. c: Flair image presented slightly high signal with blurred boundary. d and e:Diffusion weighted imaging (DWI) suggested limited diffusion of some lesions. f:Enhanced MTI suggested mild enhancement of some white matter lesions.g and h:There was no obvious abnormality on brain vessel MRI.
Figure 2 : Several infiltrative lesions involved the bilateral frontal, parietal, temporal lobes, right cerebellar hemisphere and left pontile of the patient 2. a and d: T1WI showed slightly low signal. b and e: T2WI displayed high signal. c and f: flair image revealed slightly high signal.
Figure 3 : Several infiltrative lesions involved the bilateral frontal, parietal, temporal lobes, right cerebellar hemisphere and left pontile of the patient 2 (1 month after treatment).a.b,c: the abnormal signal in white matter area was slightly improved compared with Figure 2. d,e,f: the cerebellar hemisphere showed a 2.5 cm with contrast enhancement.