Figure 5: STRING networks for pejus and pessimum stress stages
and network and correlation graphs of proteins with expression patterns
highly correlated with blood osmolality. a) Networks with more
than three nodes for all significantly regulated proteins found in the
12-week exposure to 75g/kg salinity representing pejus level salinity
stress. Protein names in red were upregulated, those in blue were
downregulated, and those outlined in red were upregulated in this
treatment while being significantly downregulated in extended exposures
to MP at 85g/kg and/or 105g/kg. b) Networks with more than
three nodes for significantly regulated proteins found in all four
pessimum level salinity stress treatments (14-day acclimation and
extended exposure to 85g/kg and 105g/kg). Legend indicates the evidence
used to connect protein nodes in each network. c) STRING
network with symbols and colors corresponding with line graphs of Serpin
family proteins, proteins in the “focal adhesion” KEGG pathway, and
other proteins in the network. Network was constructed from proteins
linked with more than two other nodes that have correlation coefficient
r2>0.9 with protein fold change (FC)
versus blood osmolality (mOsm) FC of treatment over control.