KE made substantial contributions to conception and design, acquisition of data, analysis and interpretation of data; he has been involved in drafting the manuscript and revising it critically for important intellectual content. AL made substantial contributions to interpretation of data and she has beeninvolved in drafting the manuscript and revising it critically for important intellectual content. AB and AL made substantial contributions to conception and design and acquisition of data; they has been involved in drafting the manuscript.

All authors read and approved the final version of the manuscript