Methods
The study was carried out in Kayseri State Hospital, Endocrinology and
Cardiology clinics from January 2019 to July 2020. Fifty PHPT patients
(45 females, 5 males) aged 30-75 years and 38 controls (35 females, 3
males) aged 31-73 years were included in the study.
In addition to a detailed medical history from all patients, physical
examination, 12-lead electrocardiography, complete blood count and serum
biochemistry test were performed. The presence of classical
cardiovascular risk factors, including hypertension, diabetes mellitus
and hyperlipidemia, was assessed. Detailed transthoracic
echocardiographic examination was performed on all patients.
Patients with a history of ischemic heart disease, patients with
segmental or global wall motion disorders, patients with evidence of
moderate to severe valvular heart disease on echocardiography, and
patients with structural heart disease, multiple endocrine neoplasms,
parathyroid cancer, thyroid cancer or hyperparathyroidism-jaw tumor
syndrome, renal failure, and serious comorbidities were excluded from
the study.
There was no significant difference between the patients and the control
group in cardiovascular risk factors such as age, gender, hypertension
frequency, diabetes mellitus, and hyperlipidemia.
Type 2 diabetes mellitus (T2DM), hypertension and Hyperlipidemia were
defined as previously described (7).