Methods
The study was carried out in Kayseri State Hospital, Endocrinology and Cardiology clinics from January 2019 to July 2020. Fifty PHPT patients (45 females, 5 males) aged 30-75 years and 38 controls (35 females, 3 males) aged 31-73 years were included in the study.
In addition to a detailed medical history from all patients, physical examination, 12-lead electrocardiography, complete blood count and serum biochemistry test were performed. The presence of classical cardiovascular risk factors, including hypertension, diabetes mellitus and hyperlipidemia, was assessed. Detailed transthoracic echocardiographic examination was performed on all patients.
Patients with a history of ischemic heart disease, patients with segmental or global wall motion disorders, patients with evidence of moderate to severe valvular heart disease on echocardiography, and patients with structural heart disease, multiple endocrine neoplasms, parathyroid cancer, thyroid cancer or hyperparathyroidism-jaw tumor syndrome, renal failure, and serious comorbidities were excluded from the study.
There was no significant difference between the patients and the control group in cardiovascular risk factors such as age, gender, hypertension frequency, diabetes mellitus, and hyperlipidemia.
Type 2 diabetes mellitus (T2DM), hypertension and Hyperlipidemia were defined as previously described (7).