REFERENCES:
1. Qaddoumi I, Sultan I, Broniscer A. Pediatric low-grade gliomas and
the need for new options for therapy: Why and how? Cancer Biol
Ther. 2009;8(1):4-10.
2. Mistry M, Zhukova N, Merico D, Rakopoulos P, Krishnatry R, Shago M,
et al. BRAF mutation and CDKN2A deletion define a clinically distinct
subgroup of childhood secondary high-grade glioma. J Clin Oncol.2015 Mar 20;33(9):1015-22.
3. Lassaletta A, Zapotocky M, Mistry M, Ramaswamy V, Honnorat M,
Krishnatry R, et al. Therapeutic and Prognostic Implications of BRAF
V600E in Pediatric Low-Grade Gliomas. J Clin Oncol. 2017 Sep
1;35(25):2934-2941.
4. Bluml S, Panigrahy A, Laskov M, Dhall G, Krieger MD, Nelson MD, et
al. Elevated citrate in pediatric astrocytomas with malignant
progression. Neuro Oncol. 2011;13(10):1107-17.
5. Choi C, Ganji SK, Madan A, Hulsey KM, An Z, Zhang S, et al. In vivo
detection of citrate in brain tumors by 1H magnetic resonance
spectroscopy at 3T. Magn Reson Med. 2014;72(2):316-23.
6. Sturm D, Witt H, Hovestadt V, Khuong-Quang DA, Jones DT, Konermann C,
et al. Hotspot mutations in H3F3A and IDH1 define distinct epigenetic
and biological subgroups of glioblastoma. Cancer Cell.2012;22(4):425-37.
7. Schwartzentruber J, Korshunov A, Liu XY, Jones DT, Pfaff E, Jacob K,
et al. Driver mutations in histone H3.3 and chromatin remodelling genes
in paediatric glioblastoma. Nature. 2012;482(7384):226-31.
8. Wu G, Broniscer A, McEachron TA, Lu C, Paugh BS, Becksfort J, et al.
Somatic histone H3 alterations in pediatric diffuse intrinsic pontine
gliomas and non-brainstem glioblastomas. Nat Genet.2012;44(3):251-3.
9. Kallappagoudar S, Yadav RK, Lowe BR, Partridge JF. Histone H3
mutations–a special role for H3.3 in tumorigenesis?Chromosoma . 2015;124(2):177-89.
10. Gielen GH, Gessi M, Hammes J, Kramm CM, Waha A, Pietsch T. H3F3A
K27M mutation in pediatric CNS tumors: a marker for diffuse high-grade
astrocytomas. Am J Clin Pathol. 2013;139(3):345-9.
11. Hochart A, Escande F, Rocourt N, Grill J, Koubi-Pick V, Beaujot J,
et al. Long survival in a child with a mutated K27M-H3.3 pilocytic
astrocytoma. Ann Clin Transl Neurol . 2015;2(4):439-43.
12. Orillac C, Thomas C, Dastagirzada Y, Hidalgo ET, Golfinos JG, Zagzag
D, et al. Pilocytic astrocytoma and glioneuronal tumor with histone H3
K27M mutation. Acta Neuropathol Commun . 2016;4(1):84.
13. Chan KM, Fang D, Gan H, Hashizume R, Yu C, Schroeder M, et al. The
histone H3.3K27M mutation in pediatric glioma reprograms H3K27
methylation and gene expression. Genes Dev . 2013;27(9):985-90.
14. Bottomley PA, Foster TH, Leue WM. Chemical imaging of the brain by
NMR. Lancet . 1984;1(8386):1120.
15. Provencher SW. Estimation of metabolite concentrations from
localized in vivo proton NMR spectra. Magn Reson Med.1993;30(6):672-9.
16. Louis DN, Perry A, Reifenberger G, von Deimling A, Figarella-Branger
D, Cavenee WK, et al. The 2016 World Health Organization Classification
of Tumors of the Central Nervous System: a summary. Acta
Neuropathol. 2016;131(6):803-20.
17. Buczkowicz P, Bartels U, Bouffet E, Becher O, Hawkins C.
Histopathological spectrum of paediatric diffuse intrinsic pontine
glioma: diagnostic and therapeutic implications. Acta
Neuropathol. 2014;128(4):573-81.
18. Gessi M, Gielen GH, Dreschmann V, Waha A, Pietsch T. High frequency
of H3F3A (K27M) mutations characterizes pediatric and adult high-grade
gliomas of the spinal cord. Acta Neuropathol . 2015;130(3):435-7.
19. Korshunov A, Ryzhova M, Hovestadt V, Bender S, Sturm D, Capper D, et
al. Integrated analysis of pediatric glioblastoma reveals a subset of
biologically favorable tumors with associated molecular prognostic
markers. Acta Neuropathol . 2015;129(5):669-78.
20. Justin N, Zhang Y, Tarricone C, Martin SR, Chen S, Underwood E, et
al. Structural basis of oncogenic histone H3K27M inhibition of human
polycomb repressive complex 2. Nat Commun. 2016;7:11316.
21. Pages M, Beccaria K, Boddaert N, Saffroy R, Besnard A, Castel D, et
al. Co-occurrence of histone H3 K27M and BRAF V600E mutations in
paediatric midline grade I ganglioglioma. Brain Pathol.2018;28(1):103-11.