Drug Phenotype variant n patients Drugs triggering PGx testing Clinical recommendation to change triggering drugs
metoprolol CYP2D6 IM 4 clopidogrel 1
metoprolol CYP2D6 IM 1 opioids 1
metoprolol CYP2D6 UM 1 clopidogrel 0
atorvastatin SLCO1B1 decreased function 1 opioids 1
atorvastatin SLCO1B1 decreased function 3 clopidogrel 1
rosuvastatin SLCO1B1 decreased function 1 clopidogrel 0
simvastatin SLCO1B1 decreased function 1 clopidogrel 1
phenprocoumon CYP2C9 NM, CYP4F2 PM, VCORC1 decreased function 1 clopidogrel 1
phenprocoumon CYP2C9 NM, CYP4F2 PM, VCORC1 normal function 1 clopidogrel 1
phenprocoumon CYP2C9 PM, CYP4F2 NM, VKORC1 decreased function 1 clopidogrel 1
phenprocoumon CYP2C9 IM, CYP4F2 IM, VKORC1 decreased function 2 clopidogrel 1
phenprocoumon CYP2C9 NM, CYP4F2 NM, VKORC1 decreased function 1 clopidogrel 1
Oxycodon CYP2D6 IM 2 clopidogrel 0
Oxycodon CYP2D6 IM 1 opioids 1
Oxycodon CYP2D6 IM 1 polypsychopharmacotherapy 0
Tramadol CYP2D6 IM 1 polypsychopharmacotherapy 0
pantoprazol CYP2C19 UM 1 opioids 1
pantoprazol CYP2C19 UM 2 clopidogrel 0
tacrolimus CYP3A5 expresser 1 opioids 0
flupenthixol CYP2D6 IM 1 polypsychopharmacotherapy 1
Sertralin CYP2C19 UM 1 polypsychopharmacotherapy 0
Bisoprolol CYP2D6 IM 1 screening na, PGx screening
atorvastatin CYP2D6 IM 1 screening na, PGx screening
amitriptylin CYP2D6 PM 1 screening na, PGx screening