CYP2D6 UM/NM
CYP2D6 IM
CYP2D6 PM
|
133 (276)
99 (204)
27 (66)
|
6.0 (5.8, 6.3)
6.5 (6.2, 6.7)
7.9 (7.5, 8.4)
|
0 (0)
0.45 (0.16)
1.9 (0.24)
|
-
0.006
<0.001
|
58 (53, 63)
49 (44, 55)
45 (35, 56)
|
0 (0)
-8.8 (3.8)
-13 (5.9)
|
-
0.022
0.029
|
2.11 (1.9, 2.3)
2.77 (2.5, 3.0)
4.37 (3.9, 4.8)
|
0 (0)
0.66 (0.17)
2.26 (0.26)
|
-
<0.001
<0.001
|
0 (0)
0.50 (0.26, 0.96)
0.34 (0.10, 1.1)
|
0 (0)
-0.70 (0.33)
-1.1 (0.60)
|
-
0.037
0.068
|
#The values are presented as ln-transformed values to ensure normal
distribution. The average values were calculated with linear mixed model
with age as covariate (the value of age is shown as *23.4 years).
CYP, cytochrome P450; UM, ultra-rapid metabolizers; NM, normal
metabolizers; IM, intermediate metabolizers; PM, poor metabolizers; CI,
95% confidence intervals; SE, standard error
|
#The values are presented as ln-transformed values to ensure normal
distribution. The average values were calculated with linear mixed model
with age as covariate (the value of age is shown as *23.4 years).
CYP, cytochrome P450; UM, ultra-rapid metabolizers; NM, normal
metabolizers; IM, intermediate metabolizers; PM, poor metabolizers; CI,
95% confidence intervals; SE, standard error
|
#The values are presented as ln-transformed values to ensure normal
distribution. The average values were calculated with linear mixed model
with age as covariate (the value of age is shown as *23.4 years).
CYP, cytochrome P450; UM, ultra-rapid metabolizers; NM, normal
metabolizers; IM, intermediate metabolizers; PM, poor metabolizers; CI,
95% confidence intervals; SE, standard error
|
#The values are presented as ln-transformed values to ensure normal
distribution. The average values were calculated with linear mixed model
with age as covariate (the value of age is shown as *23.4 years).
CYP, cytochrome P450; UM, ultra-rapid metabolizers; NM, normal
metabolizers; IM, intermediate metabolizers; PM, poor metabolizers; CI,
95% confidence intervals; SE, standard error
|
#The values are presented as ln-transformed values to ensure normal
distribution. The average values were calculated with linear mixed model
with age as covariate (the value of age is shown as *23.4 years).
CYP, cytochrome P450; UM, ultra-rapid metabolizers; NM, normal
metabolizers; IM, intermediate metabolizers; PM, poor metabolizers; CI,
95% confidence intervals; SE, standard error
|
#The values are presented as ln-transformed values to ensure normal
distribution. The average values were calculated with linear mixed model
with age as covariate (the value of age is shown as *23.4 years).
CYP, cytochrome P450; UM, ultra-rapid metabolizers; NM, normal
metabolizers; IM, intermediate metabolizers; PM, poor metabolizers; CI,
95% confidence intervals; SE, standard error
|
#The values are presented as ln-transformed values to ensure normal
distribution. The average values were calculated with linear mixed model
with age as covariate (the value of age is shown as *23.4 years).
CYP, cytochrome P450; UM, ultra-rapid metabolizers; NM, normal
metabolizers; IM, intermediate metabolizers; PM, poor metabolizers; CI,
95% confidence intervals; SE, standard error
|
#The values are presented as ln-transformed values to ensure normal
distribution. The average values were calculated with linear mixed model
with age as covariate (the value of age is shown as *23.4 years).
CYP, cytochrome P450; UM, ultra-rapid metabolizers; NM, normal
metabolizers; IM, intermediate metabolizers; PM, poor metabolizers; CI,
95% confidence intervals; SE, standard error
|
#The values are presented as ln-transformed values to ensure normal
distribution. The average values were calculated with linear mixed model
with age as covariate (the value of age is shown as *23.4 years).
CYP, cytochrome P450; UM, ultra-rapid metabolizers; NM, normal
metabolizers; IM, intermediate metabolizers; PM, poor metabolizers; CI,
95% confidence intervals; SE, standard error
|
#The values are presented as ln-transformed values to ensure normal
distribution. The average values were calculated with linear mixed model
with age as covariate (the value of age is shown as *23.4 years).
CYP, cytochrome P450; UM, ultra-rapid metabolizers; NM, normal
metabolizers; IM, intermediate metabolizers; PM, poor metabolizers; CI,
95% confidence intervals; SE, standard error
|
#The values are presented as ln-transformed values to ensure normal
distribution. The average values were calculated with linear mixed model
with age as covariate (the value of age is shown as *23.4 years).
CYP, cytochrome P450; UM, ultra-rapid metabolizers; NM, normal
metabolizers; IM, intermediate metabolizers; PM, poor metabolizers; CI,
95% confidence intervals; SE, standard error
|
#The values are presented as ln-transformed values to ensure normal
distribution. The average values were calculated with linear mixed model
with age as covariate (the value of age is shown as *23.4 years).
CYP, cytochrome P450; UM, ultra-rapid metabolizers; NM, normal
metabolizers; IM, intermediate metabolizers; PM, poor metabolizers; CI,
95% confidence intervals; SE, standard error
|
#The values are presented as ln-transformed values to ensure normal
distribution. The average values were calculated with linear mixed model
with age as covariate (the value of age is shown as *23.4 years).
CYP, cytochrome P450; UM, ultra-rapid metabolizers; NM, normal
metabolizers; IM, intermediate metabolizers; PM, poor metabolizers; CI,
95% confidence intervals; SE, standard error
|
#The values are presented as ln-transformed values to ensure normal
distribution. The average values were calculated with linear mixed model
with age as covariate (the value of age is shown as *23.4 years).
CYP, cytochrome P450; UM, ultra-rapid metabolizers; NM, normal
metabolizers; IM, intermediate metabolizers; PM, poor metabolizers; CI,
95% confidence intervals; SE, standard error
|