3.1.1 DENV regulation of apoptosis
Dengue virus is a serious arbovirus and the most lethal among all Flavivirus members. There are four distinct DENV strains (DENV 1-4) in serology. Dengue infection may cause diverse pathogenic conditions, ranging from mild-flu like febrile syndrome (dengue fever) to very serious conditions caused by infection with the second serotype, the dengue hemorrhagic fever (DHF) or the dengue shock syndrome (DSS)(Courageot, Catteau, & Desprès, 2003).