Conclusion
In conclusion, we demonstrated a significant and independent association between serum periostin and asthma severity in children. Our findings highlight the diagnostic role of periostin in identifying children with severe asthma. Further studies are needed to better demonstrate the role of periostin in the asthma pathogenesis and clinical utility for the physicians dealing with children with asthma.
Acknowledgements: We are extremely grateful to all the patients and their families who took part in this study. We would also like to acknowledge the hard work and dedication of the study team, which includes physicians, laboratory technicians and nurses.